A Crack in Creation
Gene Editing and the Unthinkable Power to Control Evolution
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A Crack in Creation
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Narrated by:
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Erin Bennett
About this listen
A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril.
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers and will help address the world's hunger crisis. Yet even the tiniest changes to DNA could have myriad unforeseeable consequences - to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create "better" humans. Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?
©2017 Jennifer A. Doudna and Samuel H. Sternberg (P)2017 Audible, Inc.Listeners also enjoyed...
What listeners say about A Crack in Creation
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Overall4 out of 5 stars
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Performance5 out of 5 stars
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Story4 out of 5 stars
- M. Griffiths
- 15-08-17
Gene editing introduction
From the horse's mouth, this book runs thru the discovery of truly transformational biology. Basic concepts are well explained for the uninitiated and the story is both incredibly important and interesting. The author's presentation of her work was not unlikeable and seemed fair - she has been accused of claiming all the credit.
Why not 5 stars? It is a little repetitive and an accompanying pdf is invaluable for this type of book.
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1 person found this helpful
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Overall3 out of 5 stars
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Performance4 out of 5 stars
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Story4 out of 5 stars
- Alejandro Celery
- 02-05-24
Very technical in the first half
Has a lot of technical details about what crispr is and how it works, the second half is more informative.
Also it's from 2016, so the panorama it presents in the second half might be dated.
Otherwise a good listen.
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Overall4 out of 5 stars
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Performance4 out of 5 stars
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Story5 out of 5 stars
- Anonymous User
- 19-12-21
Highly informotive, the new method is well explain
This book is a nice story of how researchers discovered the simplest form of CRISPR and used it for gene editing. Unfortunately, little was said about the initial discovery of CRISPR. In my opinion, the author greatly overestimates her contribution to the field, hence the story is a bit one-sided. As I understood, most research was actually done by two very smart European postdocs. I'd like to her their story. I guess this would be more like Watson's DNA book with ups and downs, rather than a smooth explanation of things by a big boss.
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Elitsa Penkova
- 16-07-21
Excellent book
Very engaging book, discussing the two sides of the debate on the future of gene editing. Highly recommend for both science as well as lay audience.
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Allan Paterson
- 28-04-19
Clear and informative
I was concerned that the biology within this would have been too complex to understand and whilst I don't think for one second I fully understood each point overall this helped me much better understand this amazing break through and the potential it has for us as a species. Enjoyable and well worth a listen.
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1 person found this helpful
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Craig
- 05-11-17
Outstanding Science !
Whilst the science of CRISPR will change everything....and I mean everything, this book is superb at putting the case for both the technical issues and the societal.
One of the best books I have read in a long time!
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Overall3 out of 5 stars
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Performance4 out of 5 stars
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Story3 out of 5 stars
- Pyrex
- 20-11-24
Annoying narrative (of author)
Although perhaps intended to he autobiographical on some scale, the somewhat arrogant, self-important narrative unfortunately masks the underlying interesting science being described.
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Overall2 out of 5 stars
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Performance3 out of 5 stars
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Story2 out of 5 stars
- Anonymous User
- 21-11-18
better science than story
Jennifer is clearly a better scientist than storyteller. some sections, specially the future prospects look overly extended
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