In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Mike Israetel, an exercise physiologist and co-founder of Renaissance Periodization, to break down the science of sustainable fat loss and muscle gain. We explore the essential strategies for transforming your physique without falling for quick fixes or fad diets. From macronutrient distribution to the critical role of resistance training, Dr. Israetel offers practical, science-backed guidance for anyone looking to optimize their health and fitness. From macronutrients to supplements, we cover it all!

We dive into:

• Why fat loss is often misunderstood and overcomplicated
• The key principles of calorie balance and macronutrient needs
• Strategies to preserve muscle while losing fat
• How to tailor your diet and activity level for sustainable results
• The revolutionary role of GLP-1 agonists like Ozempic

If you’ve ever struggled to make sense of dieting myths or want a clear roadmap to achieving your fitness goals, this episode delivers the tools you need to succeed.

Who is Dr. Mike Israetel?

Dr. Mike Israetel is a leading expert in exercise physiology and nutrition science. With a PhD in Sport Physiology from East Tennessee State University, he has dedicated his career to teaching evidence-based principles for fitness and nutrition. As the co-founder of Renaissance Periodization, he has helped countless individuals achieve their goals through practical and sustainable methods. Dr. Israetel is also a competitive bodybuilder, author, and sought-after speaker in the fitness industry.

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Find Dr. Mike Israetel at:

Instagram: @drmikeisraetel

Youtube: https://www.youtube.com/@RenaissancePeriodization/videos

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Join Dr. Gabrielle Lyon and Dr. Russell Surasky, a neurologist and addiction specialist, as they delve into the science of addiction. From the devastating effects of opioids and fentanyl to the impact of dopamine pathways, this episode explores the physiological, psychological, and societal challenges of addiction. Discover actionable strategies, the importance of stigma reduction, and groundbreaking treatment options that save lives.

📍 Chapter Timestamps:

00:00 - Introduction: Why Addiction Needs Urgent Attention

03:42 - The Science of Addiction: What Happens in the Brain

12:30 - Genetic Susceptibility and Environmental Triggers

21:08 - The Fentanyl Crisis: A Deadly Epidemic

32:50 - Medication-Assisted Treatment: Myths and Facts

41:30 - Reducing Stigma: Language and Societal Perception

50:12 - Real-World Strategies for Recovery

👉 Don't miss this in-depth conversation that could save a life. Subscribe for more critical insights!

🔗 Resources Mentioned:

Dr. Gabrielle Lyon’s Website: https://drgabriellelyon.com/

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Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Join Dr. Gabrielle Lyon and Dr Christie Ballantyne, one of the world’s leading cardiologists, for an insightful conversation on the science behind cardiovascular health, metabolic wellness, and disease prevention. In this episode, Dr. Ballantyne shares groundbreaking research, the role of genetics, and practical steps you can take to optimize heart health. Whether it’s through diet, exercise, or understanding your unique health profile, this discussion is packed with actionable strategies to help you live a longer, healthier life.

💡 Key Topics Covered:

• How genetics influence heart disease risk
• The power of lifestyle changes for heart and metabolic health
• Breakthroughs in cardiovascular research you need to know

📌 Timestamps:

00:00 - Introduction

02:15 - Why genetics play a role in heart disease

07:45 - The link between lifestyle and cardiovascular health

15:20 - Cutting-edge studies in heart and metabolic wellness

20:50 - Practical tips to prevent heart disease

28:00 - The future of cardiovascular medicine

🔗 Resources Mentioned:

Dr. Gabrielle Lyon’s Website

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Dive into an extraordinary conversation with Dr. Gabrielle Lyon and Dr. Jamie Baum, Associate Professor and Director of the Center for Human Nutrition at the University of Arkansas. In this episode, we explore revolutionary topics:

The role of skeletal muscle in appetite regulation.

Cutting-edge research on perimenopause and postmenopause nutrition.

How dietary protein impacts health and weight management.

Surprising findings on protein supplementation and sleep quality.

The science behind muscle-brain crosstalk and its effects on aging.

Dr. Baum shares her journey into research focused on women's health, the underrepresentation of women in protein science, and why muscle health is key to longevity.

Learn about the latest studies on protein types (whey, casein, soy), appetite signals, and why muscle may be the organ of the future.

💡 Key Takeaway: Your muscle health isn’t just about strength—it’s a driver of overall well-being and longevity.

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Find Dr. Jamie Baum at:

- Website: https://food-science.uark.edu/people/faculty/uid/baum/name/Jamie+I.+Baum/

Find me at:

- Instagram: @drgabriellelyon

- Tik Tok: @drgabriellelyon

- Facebook: facebook.com/doctorgabriellelyon

Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon is joined by Dr. Donald Layman, a world-renowned expert in protein metabolism and a pioneer in the field of nutritional science. With over 20 years of mentorship between them, Dr. Layman and Dr. Lyon dive deep into the flaws, myths, and future of U.S. Dietary Guidelines, offering a clear path to better health through smarter dietary decisions.

Dr. Layman shares his revolutionary perspective on why protein intake should focus on essential amino acids, how carbohydrates—not fats—are driving metabolic disease, and why outdated nutrition guidelines continue to mislead the public. From breaking down dietary biases to advocating for personalized nutrition, this episode is a must-listen for anyone striving for optimal health.

We dive into:

• The history and evolution of the U.S. Dietary Guidelines, from the Food Pyramid to MyPlate.
• Why "protein" as we know it is an outdated concept—and how essential amino acids are the real focus.
• How processed carbohydrates are the primary drivers of obesity, diabetes, and heart disease.
• The truth about saturated fats and cholesterol—and why the science contradicts public policy.
• How low-carb, high-protein diets outperform standard dietary recommendations in nearly every metric.
• Why nutrient-dense animal proteins are irreplaceable, despite plant-based advocacy.

Who is Dr. Donald Layman?

Dr. Donald Layman is a globally recognized leader in protein metabolism and nutritional science. As Professor Emeritus at the University of Illinois, his groundbreaking research has redefined how we understand the role of protein and amino acids in health and aging. With over 40 years of experience, Dr. Layman has published extensively on topics ranging from muscle metabolism to dietary recommendations.

A long-time mentor and collaborator of Dr. Gabrielle Lyon, Dr. Layman is a trusted voice in advocating for evidence-based dietary practices. His work continues to influence both clinical applications and public health policies worldwide.

• Apply to become a patient - https://drgabriellelyon.com/new-patient-inquiry/
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Find Dr. Don Layman at:

- Website: https://metabolictransformation.com/meet-dr-donald-k-layman/

Find me at:

- Instagram: @drgabriellelyon

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In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to explore the science, benefits, and future of testosterone therapy. Shalin has been a driving force behind bringing Kyzatrex, an FDA-approved oral testosterone, to market—making testosterone therapy more accessible and effective for both men and women. From breaking down misconceptions to advocating for better access to hormone therapy, this conversation sheds light on how testosterone plays a crucial role in overall health and wellness.

Shalin shares his journey, discussing how his background in investments and his drive to bring valuable but overlooked health solutions to the mainstream led him to develop Kyzatrex. They dive into the challenges he faced in bringing this groundbreaking therapy to market, and how Marius Pharmaceuticals is striving to change the narrative around testosterone through education and advocacy.

We dive into:

• The common myths about testosterone and its true role in health
• Why oral testosterone is a game-changer, providing a convenient and safe alternative to injections
• The importance of testosterone for women’s health, from muscle mass to mood and cognitive function
• How testosterone therapy can positively impact mental health and metabolic conditions, including diabetes
• The mission behind The Testosterone Project and efforts to make testosterone testing standard practice

Tune in to hear Shalin’s insights into the future of hormone therapy and the steps his team is taking to improve access and education around testosterone. This episode is a must-listen for anyone interested in health optimization, longevity, or understanding how testosterone therapy can impact overall quality of life.

Who is Shalin Shah?

Shalin Shah is a distinguished leader in the field of metabolic health, specializing in testosterone replacement therapy. As the Chief Executive Officer of Marius Pharmaceuticals, he was instrumental in the development and FDA approval of KYZATREX® (testosterone undecanoate) CIII Capsules, an oral testosterone treatment for adult men with low or no testosterone levels due to certain medical conditions.

With a global investment background, Shalin transitioned into healthcare with a mission to revolutionize the industry through metabolic health. His leadership at Marius Pharmaceuticals is marked by innovative strategies that prioritize consumer access and education. Under his guidance, KYZATREX has been launched via consumer-focused channels that include preeminent national healthcare institutions, private-equity backed medical practices, and national telemedicine platforms.

Shalin’s expertise extends beyond corporate leadership; he is an influential voice in longevity medicine and an advocate for reevaluating testosterone medication regulations. His efforts aim to reshape public perception and education on testosterone therapy and its significance for global health. He believes that oral testosterone replacement therapy has created a much-awaited paradigm shift which is critical for addressing the worldwide men’s (and women’s) health crisis, marked by declining testosterone levels and lower life expectancies. His message is that testosterone replacement therapy is not just about adding years to life, but also about adding life to years.

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Read More -...

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Heidi Somers, the founder of Buff Bunny Collection, a dynamic and empowering fitness and lifestyle brand that has taken the industry by storm. From growing up in a small town in Alaska to becoming a successful entrepreneur, Heidi’s journey is a testament to the power of resilience, self-belief, and authenticity.

Heidi opens up about her humble beginnings, including her early struggles with weight and body image, and shares how these experiences fueled her passion to help other women feel strong, confident, and stylish. She reflects on her decision to leave college and a pre-med path to pursue her dream, her challenges in starting a business from scratch, and the deep sense of purpose she finds in creating high-quality, functional activewear.

We dive into:

• How Heidi turned her personal challenges into a successful business
• The value of persistence, grit, and trusting your instincts
• Why self-care and fitness are essential for sustained success
• Practical advice for building a transparent and community-centered brand

Tune in to hear Heidi’s inspiring journey and the strategies she used to build a thriving, values-driven business. Whether you're an entrepreneur, fitness enthusiast, or just seeking a boost of motivation, this episode is packed with practical advice and empowering stories to inspire your own journey.

Who is Heidi Somers?

Heidi Somers is the founder and CEO of Buff Bunny Collection, a popular activewear brand dedicated to empowering women through fitness, fashion, and self-confidence. Growing up in a small town in Alaska, Heidi’s journey to success wasn’t easy. She faced personal challenges, including struggles with weight and self-acceptance, which fueled her passion to create a supportive community and high-quality activewear designed specifically for women. From humble beginnings on YouTube sharing fitness tips, Heidi built a multi-million dollar brand that resonates with women everywhere. Today, she’s celebrated for her transparency, grit, and dedication to helping women look and feel their best, both inside and out.

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Follow Heidi Somers -

• Instagram: https://www.instagram.com/buffbunny
• Twitter: @HeidiSomers
• YouTube: https://www.youtube.com/@heidisomers

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In this enlightening episode of the Dr. Gabrielle Lyon Show, we dive deep into the world of youth training and the crucial role it plays in long-term health and athletic development. Joined by Judd Leinhard, former Army Ranger, collegiate lineman, and expert in speed training, we explore how training children differs from adults, debunk common myths, and reveal the surprising truth about building strength and resilience in kids.

We dive into:

• Why strength training and weightlifting are safe—and even essential—for children.
• Practical advice for parents on encouraging active lifestyles and modeling healthy behavior.
• The overlooked benefits of teaching kids proper breathing and stability for better athletic outcomes.
• Insights into how children's nervous systems adapt and protect them during training.

If you're a parent, coach, or simply interested in the foundations of youth fitness and development, this episode will open your eyes to how early interventions in movement and strength training can significantly impact health and performance for years to come.

Who is Judd Lienhard?

Judd is the founder of MASS Method, a performance-based workout program dedicated to improving Movement, Athleticism, Strength, and Speed. He has worked as a Speed and Performance Coach in Austin, TX, for the past twelve years.

Judd's nontraditional approach to fitness was vastly shaped by his background as a collegiate athlete (middle linebacker at Truman State) and time in service as a US Army Ranger. During Judd's military career, he completed three deployments between Iraq and Afghanistan. Upon completion of his service obligation, Judd decided to focus his career efforts on coaching and fitness.

In addition to MASS Method, Judd coaches a private community dedicated to personal development based on his ethos: Always Be An Athlete. Judd is a proud dad, avid writer, history buff, and of course, a lifetime athlete.

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This episode is brought to you by:

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Find Judd Lienhard at -

• Instagram: www.instagram.com/juddlienhard/
• Website: www.juddlienhard.com
• YouTube: https://www.youtube.com/@juddlienhard

Find me at:

• Instagram: @drgabriellelyon
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