Longevity Supplements: Do NMN and NR Actually Work?

Read on to find out what the research says.

Overview:
In this week's episode, we dive into the popular supplements NMN and NR that are touted to increase longevity and healthspan. We break down what these supplements actually are, what the research says about their effects on muscle and physical function, and whether you should spend your money on them.

Key Takeaways:

0:45 - What are NMN and NR? Precursors to NAD+, which declines with age
2:30 - Animal studies show benefits, but what about humans?
3:45 - Results of a systematic review of RCTs in older adults on muscle strength and physical function
5:00 - Studies sponsored by industry show benefits, but lower quality evidence
6:30 - Are they worth spending your money on?

CTA: Dive into the research and decide for yourself - listen to the full episode now!

See omnystudio.com/listener for privacy information.

This episode discusses the importance of connection as the fourth pillar of mental fitness. It explores how modern lifestyles and digital interactions have led to increased loneliness and less genuine human connection. Through personal anecdotes, carly emphasises the value of real-life interactions over digital connections and encourages listeners to actively seek out 'micro connections' in their daily lives. A suggested journaling exercise based on the Japanese practice of Naikan helps reflect on received and given connections to improve well-being. The episode concludes with a call to ramp up meaningful connections and engage children in similar practices.

00:00 Introduction to the Fourth Pillar of Mental Fitness

00:36 The Decline of Genuine Human Connection

01:51 Personal Anecdotes on Connection

03:17 The Importance of Micro Connections

04:41 Encouraging Real-World Interactions

05:24 Reflecting on Daily Connections

07:16 Conclusion and Weekly Challenge

See omnystudio.com/listener for privacy information.

In this super interesting episode, I sit down with Amelia Phillips - exercise scientist, nutritionist, and the founder of Vitality 360. Together, we explore the secrets to enhancing longevity and healthspan. Our conversation is a blend of science-backed insights and practical advice for anyone committed to living a longer, healthier, and happier life.

What You'll Learn:

1. Exercise and Longevity: Discover the importance of incorporating high-intensity training and cardiovascular workouts to boost healthspan.
2. Nutrition Insights: We dive deep into dietary patterns, emphasising a Mediterranean-style diet rich in nutrients, and discuss the misconceptions surrounding carbohydrates and protein.
3. Supplementation for Health: Amelia breaks down essential supplements for those over 40, including magnesium, collagen, creatine, vitamin D, and Omega-3 fatty acids, backed by extensive research and trials.
4. Innovative Biohacks: The benefits of VO2 max training, heat and cold therapy, and the surprising power of simple vitamin supplementation are explored.
5. Combining Interventions for Optimal Health: Learn about the synergistic effects of vitamin D, Omega-3, and exercise, backed by groundbreaking studies showing dramatic reductions in cancer risk and biological aging.

Key Takeaways:

• Foundations First: Prioritise foundational health pillars—exercise, nutrition, sleep, and mindset—before layering advanced biohacks.
• Synergistic Benefits: Combining simple interventions like vitamin D, Omega-3 supplements, and regular exercise can significantly enhance health and longevity.
• Importance of Customisation: Tailor dietary and supplementation strategies to individual needs, especially considering factors like age and health status.
• Simple Biohacks Can Be Powerful: Sometimes the most effective changes are straightforward, affordable, and accessible, such as consistent exercise and vitamin supplementation.
• Track Key Biomarkers: Regularly monitor important health markers, especially as you age, to proactively manage and optimise health.

Resources:

• Explore Amelia Phillip’s work and programs at Vitality 360 for personalised health assessments and strategies.
• Connect with Amelia Phillips on Instagram for daily insights and health tips and tune into her podcast "Healthy Her" for more great conversations.

Support the Podcast:

If you found these insights valuable, please consider subscribing, rating, and leaving a review on your favourite podcast platform. Your support helps us bring transformative conversations to more listeners.

Support and Share:

Share this episode with family or friends who may benefit from these life-enhancing strategies. A small change could lead to a big health impact!

01:07 The Importance of Continuous Learning

02:17 A Funny Smurf Story

05:19 Diving into Longevity and Health Trends

06:27 The Ladder Approach to Health

09:07 Foundational Health Pillars

11:25 The Role of Nutrition in Longevity

21:12 Exercise and Biohacking for Midlife

27:04 Supplements for Optimal Health

40:58 Vitamin D and Omega-3 Fatty Acids

41:16 Exercise and Study Findings

42:14 Dietary Interventions and New Book

42:42 DO Health Trial and Combined Interventions

43:23 Biohacking and Nutrient Synergy

46:42 Omega-3 Index and Supplementation

51:12 Iron and Other Supplements

55:04 Hormone Replacement Therapy

58:00 Key Biomarkers to Track

01:05:54 Metabolic Syndrome and Insulin Resistance

See omnystudio.com/listener for privacy information.

In this edition of Wisdom Wednesdays, the focus is on the incredible malleability of the human heart, inspired by my personal experience with open-heart surgery. The episode delves into historic and revolutionary studies, starting with the 1966 Dallas Bedrest Study, which showcased the drastic effects of inactivity on cardiovascular health.

It then explores follow-up studies that demonstrated how structured exercise programs can not only reverse cardiac damage but also make the heart more efficient and youthful, even in middle-aged individuals.

I explore the importance of consistent, smart exercise, combining moderate aerobic activity and high-intensity intervals, to maintain a healthy heart into older age. The show concludes with a powerful reminder of the human body's need for physical activity, supported by an impactful quote from Professor Frank Booth.

00:00 Introduction and Personal Connection

00:41 The Dallas Bedrest Study: A Groundbreaking Experiment

01:41 The Impact of Bedrest and the Power of Retraining

03:54 Long-Term Effects and Follow-Up Studies

05:31 Modern Research: Reversing Cardiac Aging

06:23 Exercise Protocols for Heart Health

12:57 Key Takeaways and Final Thoughts

See omnystudio.com/listener for privacy information.

Today Carly talks about food as a foundational pillar of mental fitness. This is part 3 of the becoming mentally fit series.

Here's the link to the study:

See omnystudio.com/listener for privacy information.

In this conversation with Nick Koumalatsos, a former Marine Raider turned entrepreneur and coach, we explored the intricacies of identity, purpose, and community—all integral parts of Nick's journey from adversity to leadership. Through his experiences, Nick offers a roadmap for those looking to take control of their lives, build meaningful connections, and redefine their futures.

What You'll Learn:

• Identity and Purpose: Understand how personal identity can shape your journey and why aligning your purpose is crucial for growth.
• Facing Adversity: Learn how turning negative experiences into opportunities for growth can set you on a path to success.
• The Role of Discipline: Discover why discipline often trumps motivation, particularly in achieving long-term goals.
• Community and Connection: See how building and being part of a supportive community can transform lives and why it’s important to foster such environments.

Key Takeaways:

• It's never too late to redefine your path and take control of your life's direction.
• Success starts with personal accountability—master yourself first.
• Community is crucial for healing and growth; we thrive together, not in isolation.
• Discipline can be your greatest ally; it sees you through when motivation wanes.

Resources:

Explore Nick Koumalatsos's work at his website, which provides resources, coaching, and community for men seeking purpose and growth. Dive deeper into his mission of empowering men to lead fulfilling lives through his community, the Agoge.

Support the Podcast:

If you found this conversation insightful, please subscribe, rate, and leave a review on your favourite podcast platform. Your support helps us reach a broader audience and share these valuable discussions.

Support and Share:

If this conversation inspired you or moved you to rethink how you approach your own life's challenges, consider sharing this post with someone who might benefit from these insights. Together, let's foster a world where personal development and community support go hand in hand.

02:12 Facing Adversity and Overcoming Challenges

08:18 Joining the Military

12:10 Marine Corps Training and Setbacks

20:00 Transitioning from Military to Civilian Life

25:25 Transforming Body and Mind: My 90-Day Journey

26:23 The Birth of a GOGI: From Fitness to Mentorship

26:54 Purpose and Identity: Beyond the Marines

28:26 The Power of Forward Motion and Service

32:44 Building a Community: From Fitness to Mindset

39:07 Mastering Yourself: The Foundation of Success

40:10 Leading Your Family: Building Trust and Intentionality

42:03 Financial Mastery and Legacy Building

44:52 The Impact of Community and Brotherhood

See omnystudio.com/listener for privacy information.

See omnystudio.com/listener for privacy information.

In this episode, Carly chats with Paul about his mindset in the lead up to open heart surgery. Paul talks about the difference between a challenge or a threat orientation when it comes to life's challenges and dives into how you can train the challenge muscle to develop your mental fitness.

See omnystudio.com/listener for privacy information.